Substitution Reactions

3 Great Tips for Memorizing 200+ Organic Reactions and Mechanisms

Note: Apologies for the late article, but I had to spend several days writing this article in order to come up with a comprehensive list of tips to aid in the memorization of the organic reactions and mechanisms. I’ll be back to a regular posting sche…

47 Common Named Substitution Reactions

{getToc} $title={Table of Contents} Coupling Reactions Castro-Stephens Coupling Coupling of alkynyl cuprates and aryl halides. Friedel-Crafts Acylation Coupling of aryls and acyl halides with Lewis acid catalyst. Friedel-Crafts Alkylation Coupling of …

6 Nucleophilic Aromatic Substitution Mechanisms

{getToc} $title={Table of Contents} Introduction Benzene is a nucleophile. This is why it can undergo electrophilic aromatic substitution reactions. However, what about nucleophilic aromatic substitution reactions?  Today, we will be learning about th…

Electrophilic Aromatic Substitution (Part 3)

{getToc} $title={Table of Contents} Recap The previous article was very recent, and some advanced concepts building on the foundational ones were raised. In this article, we will no longer simply stick to the discussion of concepts; rather, we will be…

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